O-304 (100mg x 30 Capsules)

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O-304 is a synthetic small-molecule research compound developed to modulate cellular senescence-associated pathways. It acts by influencing DNA damage response, SIRT1 signaling, and collagen synthesis in experimental models of aging. O-304 is used in preclinical studies investigating epigenetic regulation, extracellular matrix remodeling, and molecular mechanisms of cellular longevity.

References:
Di Micco R et al., Cell Biol, 2021
Alves-Fernandes DK et al., DNA Repair (Amst), 2019
Shreeya T et al., Ageing Res Rev, 2024

These capsules are provided exclusively as inert containers for the dry transport, storage, and handling of laboratory research materials. They are not dosage forms and are not intended for ingestion or administration. They must not be used as drug delivery systems, consumed, or administered in any form. For Research Use Only: Not for use in humans or animals. Not for diagnostic or therapeutic purposes.

Peptide Sciences has changed the name of its peptide, but you may receive product labeled with the old name, OS-01. Any existing stock displaying OS-01 is not affiliated with, endorsed by, approved by, or otherwise associated with OneSkin’s OS-01 products and registered OS-01® trademark

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What is O-304?

(also called ATX-304) is a synthetic small-molecule research compound developed as a pan-AMPK activator.

AMPK (AMP-activated protein kinase) is a key enzyme involved in:

  • Energy metabolism
  • Glucose regulation
  • Fat oxidation
  • Cellular “energy sensing”

O-304 is studied because it can activate AMPK without lowering cellular ATP levels, which is different from older compounds like metformin. (invivochem.com)


Why it’s called an “exercise-mimetic”

Research descriptions often refer to O-304 as an “exercise-like” metabolic compound because AMPK activation is normally triggered by:

  • Physical exercise
  • Calorie restriction
  • Energy depletion in cells

Studies investigate effects such as:

  • Improved insulin sensitivity
  • Increased fat oxidation
  • Reduced liver fat in metabolic models (peptidesmaxxing.com)

What “100mg x 30 capsules” actually means

A product labeled:

👉 O-304 100mg (30 capsules)

typically refers to:

  • A capsule-based research formulation of a lab compound
  • Each capsule containing a measured amount of O-304
  • Intended for laboratory or research use only

Important: there is no approved consumer or supplement use standard for O-304.

Most suppliers explicitly state:

“Research use only, not for human consumption.” (Peptides.GG)


What research is focused on

O-304 is mainly studied in metabolic and cardiovascular research, including:

1. Metabolic health models

  • Insulin resistance
  • Glucose regulation
  • Type 2 diabetes pathways

2. Fat metabolism

  • Lipid oxidation
  • Adipose tissue energy use

3. Liver metabolism

  • Fat accumulation (NAFLD research models)
  • Hepatic AMPK signaling

4. Cardiovascular research

  • Cholesterol regulation pathways
  • Energy balance in heart tissue

Important reality check

Even though it is widely discussed online:

  • ❌ Not FDA-approved
  • ❌ Not a dietary supplement
  • ✔ Only exists in research chemical context

Some sources even describe it as a clinical-development metabolic research compound, not a finished product. (Swiss Chems Lab)


Risks of “buy O-304 capsules” listings

Common issues include:

  • No pharmaceutical manufacturing standards
  • Unknown stability in capsule form
  • No human safety or dosing validation
  • Mislabeling or inconsistent concentration claims

Even “COA verified” labels don’t mean it’s approved for use in humans.


SEO strategy (important if you’re building content)

To rank safely and avoid restrictions, avoid:

Instead use:

  • “O-304 (ATX-304): What It Is and How It Works”
  • “O-304 AMPK Activator Explained (Research Guide)”
  • “O-304 vs Metformin vs AICAR Comparison”

This helps you:

  • Capture high-intent informational traffic
  • Stay compliant with ad policies
  • Build authority in metabolic research SEO

Bottom line

is a research AMPK-activating compound studied for metabolic regulation, fat oxidation, and insulin sensitivity pathways, but “100mg capsule” products are strictly research materials—not approved supplements or medications.


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