Ipamorelin (2mg x 10), CJC-1295 no DAC (2mg x 10)

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Ipamorelin and CJC-1295 no DAC (Mod GRF 1-29) are synthetic research peptides used together in experimental models to investigate growth hormone axis regulation and somatotropic signaling mechanisms. Ipamorelin is a selective pentapeptide growth hormone secretagogue that acts as an agonist of the growth hormone secretagogue receptor (GHS-R1a), activating Gq/PLC and calcium-dependent intracellular signaling involved in GH release while demonstrating minimal interaction with other pituitary hormones in preclinical systems. CJC-1295 no DAC is a stabilized analog of growth hormone–releasing hormone (GHRH 1-29) that selectively activates the GHRH receptor, stimulating adenylate cyclase and cAMP-mediated signaling in pituitary somatotrophs. Preclinical research employs the combined activation of GHS-R1a and GHRH receptors to examine synergistic GH secretion, hypothalamic–pituitary feedback mechanisms, and endocrine receptor pharmacology in controlled laboratory settings.

For research use only. Not for human consumption.

References:
Bowers CY et al., Ann NY Acad Sci, 1998 865:244–249
Frohman LA et al., Endocr Rev, 2001 22(6):606–648
Svensson J et al., J Endocrinol Invest, 1998 21(9):692–699

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OVERVIEW

Ipamorelin (2 mg x 10) is a synthetic growth hormone–releasing peptide (GHRP) known for its selective stimulation of growth hormone (GH) release. It works by binding to ghrelin (GHS-R1a) receptors in the pituitary gland, encouraging the body to increase endogenous GH production. Unlike some earlier GHRPs, Ipamorelin is often described in research as having a more targeted action, with comparatively minimal influence on cortisol and prolactin levels. This selectivity has made it a subject of interest in experimental studies focused on muscle recovery, tissue repair, sleep support, and body composition. The 2 mg x 10 format typically indicates a multi-vial research supply intended for structured laboratory protocols.

CJC-1295 no DAC (2 mg x 10) is a modified growth hormone–releasing hormone (GHRH) analog designed to enhance the body’s natural pulsatile release of GH. The “no DAC” version has a shorter half-life than the DAC formulation, allowing for more controlled timing of administration in research settings. By stimulating GH release through a different receptor pathway than Ipamorelin, the two compounds are often discussed as complementary in experimental contexts. Together, they are studied for their potential synergistic effects on anabolic signaling, recovery processes, and metabolic function, while remaining classified primarily for laboratory investigation rather than general medical use.

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