FOX04-DRI 10mg (Proxofim)

$300.00

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FOXO4-DRI is a synthetic D-retro-inverso research peptide designed to selectively disrupt the FOXO4–p53 interaction, promoting senescent cell clearance in experimental systems. Composed of D-amino acids for enhanced stability, FOXO4-DRI interferes with nuclear retention of p53, inducing apoptosis of senescent phenotypes. It is utilized in studies exploring senolytic mechanisms, cellular longevity, and DNA damage response signaling.

For research use only. Not for human consumption.

References:
Kirkland JL et al., J Clin Invest, 2017;127(4):1247–1256
Yosef R et al., Aging (Albany NY), 2017;9(8):1758–1777
de Keizer PLJ, Trends Mol Med, 2017;23(9):751–762

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