IGF-1 LR3 1mg

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IGF-1 LR3 is a research peptide analog of human insulin-like growth factor 1 (IGF-1) containing a 13–amino acid N-terminal extension that enhances stability and receptor binding. It interacts with the IGF-1 receptor to activate PI3K/Akt and MAPK/ERK pathways involved in cellular growth, differentiation, and metabolic regulation. IGF-1 LR3 is used in experimental models to study peptide-mediated anabolic signaling, receptor kinetics, and tissue remodeling mechanisms.

For research use only. Not for human consumption.

References:
Yakar S et al., Endocr Rev, 2001 22(6):803–817
Bach LA et al., Mol Cell Endocrinol, 2018 473:1–9
Humbel RE et al., Eur J Biochem, 1990 190(3):445–462

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OVERVIEW

IGF-1 LR3 1 mg is a synthetic analog of insulin-like growth factor-1 (IGF-1), a hormone structurally similar to insulin that plays a central role in growth, development, and cellular repair. The “LR3” modification refers to an extended amino acid sequence and a substitution at position 3, which significantly increases its half-life and reduces its binding to IGF-binding proteins. This allows more of the compound to remain biologically active in circulation compared to natural IGF-1. In research settings, IGF-1 LR3 is studied for its ability to stimulate cell proliferation, enhance protein synthesis, and activate signaling pathways such as PI3K/Akt that are involved in muscle growth and tissue regeneration.

Because of its prolonged activity and strong receptor affinity, IGF-1 LR3 has been explored in experimental models focused on muscle hypertrophy, recovery processes, and metabolic regulation. It may influence nutrient partitioning and support anabolic signaling when evaluated under controlled laboratory conditions. However, IGF-1 pathways are also closely linked to cell growth regulation, making careful dosing and structured research protocols essential. As a result, IGF-1 LR3 is generally categorized as a research compound rather than a widely approved therapeutic agent. Ongoing scientific investigation continues to examine its biological effects, safety considerations, and long-term impact on cellular function.

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