Hexarelin (5mg x 10), CJC-1295 no DAC (5mg x 10)

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Hexarelin and CJC-1295 no DAC (Mod GRF 1-29) are synthetic research peptides used in experimental models to investigate growth hormone axis regulation and somatotropic signaling pathways. Hexarelin is a potent hexapeptide growth hormone secretagogue that binds the growth hormone secretagogue receptor (GHS-R1a), activating Gq/PLC and calcium-dependent intracellular signaling involved in GH release and peptide-mediated metabolic regulation. CJC-1295 no DAC is a stabilized analog of growth hormone–releasing hormone (GHRH 1-29) that selectively activates the GHRH receptor, stimulating adenylate cyclase and cAMP-dependent pathways in pituitary somatotrophs. Preclinical research utilizes the combined activation of GHS-R1a and GHRH receptors to study synergistic growth hormone secretion, hypothalamic–pituitary feedback loops, and endocrine receptor pharmacology.

For research use only. Not for human consumption.

References:
Camanni F et al., J Endocrinol Invest, 1998 21(9):646–654
Frohman LA et al., Endocr Rev, 2001 22(6):606–648
Ghigo E et al., Eur J Endocrinol, 2001 145(1):1–10

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OVERVIED

Hexarelin (5 mg x 10) is a synthetic growth hormone–releasing peptide (GHRP) recognized for its strong stimulation of growth hormone (GH) secretion. It binds to ghrelin (GHS-R1a) receptors in the pituitary and hypothalamus, triggering a pronounced increase in GH release. Due to its potency, Hexarelin has been explored in research settings for its potential effects on muscle development, recovery support, fat metabolism, and overall anabolic signaling. Some experimental studies have also examined its possible cardioprotective properties. Because of its intensity compared to other GHRPs, careful dosing considerations are often emphasized in research discussions to help manage potential elevations in prolactin or cortisol levels. The 5 mg x 10 format typically indicates multiple vials intended for structured research protocols.

CJC-1295 no DAC (5 mg x 10) is a modified growth hormone–releasing hormone (GHRH) analog designed to stimulate the body’s natural pulsatile GH release. The “no DAC” version has a shorter half-life, allowing for more controlled and time-specific administration compared to the longer-acting DAC variant. It is frequently referenced in performance and longevity research for its potential role in supporting lean body composition, sleep quality, and recovery. When discussed together, Hexarelin and CJC-1295 no DAC are often described as complementary compounds that activate different receptors to enhance endogenous growth hormone output through synergistic mechanisms.

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